Unfortunately, I personally don't feel that this is your best works yet, hence the mark. It's funny as hell, but the actual guts of it just seems a little rushed.

First of all, is the shading. Now, being MenInASuitcase, I would think that your pixel art would've been a little better. It's harsh, I know. But the shading on the pink one looks quite horrible and, once again, rushed. There is really no need to use non-standard dithering. In fact, standard dithering would definitely make things look so much cleaner and more appealing in this situation. The stretch of the dithering is the worst of what you've done here; it doesn't really smooth out the shades of colour on the biggie.

Second of all, the hands on the pink emote don't look great either. They look just as rushed as on the purple guy. What surprises me is that the indigo coloured emote, being bigger than the hands of the pink, is shaded much better.

Secondly, the text is alright, but not great. I like the idea of it fading in and out, but the text "ouch" seems a little unnecessary. The fading in and out is also a little choppy; the animation could be a little better.

However, the bed and the poor, little purple emote is pixelled fantastically. The animation is also great, as well as the expressions on both emotes. The tard face on the pinkie and the screaming horror on the purple emote is the true essence of emoting, and really finishes the emote off nicely, hence the 5 star for Impact. That's what gives it the lols all around.

Overall, it could be worked on a little, paticularly on the shading, but the emote still gets the laughs and message across.